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Media Articles
NUS Medicine team aims to start clinical trial of targeted therapy for deadly brain cancer in 2025
Straits Times
Engineering mini “bombers” and “cleaners” – How this startup is changing the game to treat aggressive cancers
SGInnovate
New therapy shows promise in treating deadly brain cancer, advanced abdominal cancer
Straits Times
Novel cell-based gene therapy developed in Singapore improves lives of cancer-stricken pets
Straits Times
Our Publications
Evaluating the potential of off-the-shelf engineered mesenchymal stem cells for targeted Hepatocellular Carcinoma treatment: A multisite proof-of-concept study. Biomed Pharmacother. 2024 Dec;181:117676. doi: 10.1016/j.biopha.2024.117676. Epub 2024 Nov 9. PMID: 39522266. Read more
Enhanced anti-tumor efficacy with multi-transgene armed mesenchymal stem cells for treating peritoneal carcinomatosis. J Transl Med. 2024 May 15;22(1):463. doi: 10.1186/s12967-024-05278-5. PMID: 38750559; PMCID: PMC11097589. Read more
Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment. Stem Cell Res Ther. 2022 Nov 14;13(1):519. doi: 10.1186/s13287-022-03198-z. PMID: 36376945; PMCID: PMC9663191. Read more
A highly efficient non-viral process for programming mesenchymal stem cells for gene directed enzyme prodrug cancer therapy. Sci Rep. 2020 Aug 31;10(1):14257. doi: 10.1038/s41598-020-71224-2. PMID: 32868813; PMCID: PMC7458920. Read more
A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth. Stem Cell Res Ther. 2020 Sep 11;11(1):391. doi: 10.1186/s13287-020-01899-x. PMID: 32917269; PMCID: PMC7488524. Read more